Preventing Repeat Hypoglycaemic Episodes in People with Diabetes: The Hypo Ambulance Study


Funding body East Midlands Collaboration for Leadership in Applied Health and Care
Total funding £291,952
  • Professor Kamlesh Khunti, University of Leicester
  • Professor Niro Siriwardena, University of Lincoln and East Midlands Ambulance Service NHS Trust (EMAS)
  • June James, University of Leicester
  • Anne Spaight, EMAS
  • Professor Melanie Davies, University of Leicester
  • Dr Helen Dallosso, University of Leicester
  • Dr Laura Gray, University of Leicester
  • Andy Willis, University of Leicester
  • Mohammad Iqbal, EMAS



University of Leicester

University of Lincoln

East Midlands Ambulance Service NHS Trust

Overarching aim The aim of this study is to implement and evaluate an enhanced care pathway for patients with diabetes who request an ambulance call out to treat a hypoglycaemic event.
Objectives Primary objective

  • To evaluate whether a diabetes specialist nurse led intervention following a call out of an ambulance to treat a hypoglycaemic episode increases the uptake of advice and/or a change to medication aimed at preventing hypoglycaemia in the future.

Secondary objectives

  • To collect data on rates of repeat ambulance call out, rates of cardiovascular disease (CVD), CVD related mortality and all-cause mortality,
  • To evaluate patient satisfaction with the treatment they have received.
  • Measure patient fear of hypoglycaemia, quality of life and knowledge of DVLA regulations relating to hypoglycaemia.
Methods Randomised controlled study
Outcomes The most important expected outcome will be data on effectiveness and cost-effectiveness of a diabetes specialist nurse (DSN) led intervention following a call out of an ambulance to treat a hypoglycaemic episode.
Outputs Peer reviewed publications and presentations to the health service leaders, general public, ambulance services and organisations, Department of Health, commissioners, policy experts and national and international conferences.
Impact This study aims to identify learning for ambulance services and commissioners of services on pathways for patients with hypoglycaemia. If the intervention is found to be effective this will provide the basis for a wider roll-out of the intervention to other ambulance services.



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