Improvement Science and Research Methods seminar given by Professor Graham Law: The design of clinical trials: what do the names mean?

On 22nd November 2023 Professor Graham Law gave the November Seminar entitled: The design of Clinical Trials: What do the names mean? If you missed Graham’s talk, the link to the recording is below.

You may have heard that Clinical Trials are typically conducted in phases. Graham explained some of these.

The phase, 1 to 4, indicates the stage of development and testing a drug or treatment has reached. These include Phase I (safety and dosage), Phase II (effectiveness and side effects), Phase III (large-scale effectiveness and monitoring of side effects), and Phase IV (post-marketing surveillance).

But we have found, an essential component of trial design has been the ‘Feasibility clinical trial’. This may be similar to, but often confused with, the ‘Pilot trial’. I will try to explain these also.

Graham Law is Professor in Medical Statistics in College of Social Science. He has published extensively in epidemiology and medical statistics. He has worked on many different diseases, particularly diabetes. He is co-Director of the Lincoln Clinical Trials Unit (

Graham is also the School Senior Leadership Team Chair, a member of the College Inclusion Committee and the Leads University Research Data Management Group.

His subject specialisms are: Diabetes, Trials, Sleep, Metabolic and Cardiovascular health, Ambulance services.

Leave a Reply

Your email address will not be published. Required fields are marked *